Corruption is the most oft-cited obstacle in relations between the EU and two of its eastern partners, Moldova and Ukraine. Seeping through public and private exchanges alike, systemic corruption impedes sectoral reforms—a crucial element of modernisation. The handbook offers concrete case studies from the Visegrad countries’ anti-corruption policy tracks and proposes solutions on how Moldova and Ukraine can best capitalise on the EU’s expertise, financial assistance and political momentum in anti-corruption reforms to minimise risk and optimise success.